meddlesome adj.

early 14c., "to mingle, blend, mix" (a sense now obsolete), from Old North French medler (Old French mesler, 12c., Modern French mêler) "to mix, mingle, to meddle," from Vulgar Latin *misculare (source of Provençal mesclar, Spanish mezclar, Italian mescolare, meschiare), from Latin miscere "to mix" (from PIE root *meik- "to mix").

From late 14c. as "busy oneself, be concerned with, engage in," and in the disparaging sense of "interfere or take part in inappropriately or impertinently, be officious, make a nuisance of oneself" (the notion is of meddling too much), which is the surviving sense of the word. From mid-14c. to c. 1700 it also was a euphemism for "have sexual intercourse." Related: Meddled; meddling.

word-forming element used in making adjectives from nouns or adjectives (and sometimes verbs) and meaning "tending to; causing; to a considerable degree," from Old English -sum, identical with some, from PIE root *sem- (1) "one; as one, together with." Cognate with Old Frisian -sum, German -sam, Old Norse -samr; also related to same.

"It usually indicates the possession of a considerable degree of the quality named: as mettlesome, full of mettle or spirit; gladsome, very glad or joyous" [Century Dictionary]. It is also, disguised, the ending in buxom. For the -some used with numbers (twosome, foursome, etc.), see -some (2).