"one-billionth of a gram," 1951, from nano- + gram.
Entries linking to nanogram
nano-
introduced 1947 (at 14th conference of the Union Internationale de Chimie) as a prefix for units of one thousand-millionth part (now "one-billionth"), from Greek nanos "a dwarf." According to Watkins, this is originally "little old man," from nannos "uncle," masc. of nanna "aunt" (see nana), but Beekes calls it "An onomatopoeic word of unknown origin." Earlier nano- was used as a prefix to mean "dwarf, dwarfish," and still it is used in a non-scientific sense of "very small."
gram n.
also gramme, metric unit of weight, 1797, from French gramme (18c.), from Late Latin gramma "small weight," from Greek gramma "small weight," a special use of the classical word meaning "a letter of the alphabet" (see -gram). Adopted into English about two years before it was established in France as a unit in the metric system by law of 19 frimaire, year VIII (1799). "There seems to be no possible objection to adopting the more convenient shorter form, except that the -me records the unimportant fact that the word came to us through French" [Fowler].