"having reduced tension or pressure," 1873, from hypo- + tonic.
Entries linking to hypotonic
hypo-
word-forming element meaning "under, beneath; less, less than" (in chemistry, indicating a lesser oxidation), from Greek hypo (prep. and adverb) "under, beneath; up from under; toward and under (i.e. into)," from PIE root *upo "under."
tonic adj.
1640s, "relating to or characterized by muscular tension," from Greek tonikos "of stretching," from tonos "a stretching," from PIE root *ten- "to stretch." The meaning "maintaining the healthy firmness of tissues" is recorded from 1680s, first extended 1756 to "having the property of restoring to health." Related: Tonical (1580s).