1873, "confuse," originally "to confuse with strong drink or opium" (by 1832), from be- + fuddle. An earlier word in the same sense was begunk (1725). Related: Befuddled; befuddling.
Entries linking to befuddle
be-
word-forming element of verbs and nouns from verbs, with a wide range of meaning: "about, around; thoroughly, completely; to make, cause, seem; to provide with; at, on, to, for;" from Old English be- "about, around, on all sides" (the unstressed form of bi "by;" see by (prep.)). The form has remained by- in stressed positions and in some more modern formations (bylaw, bygones, bystander).
The Old English prefix also was used to make transitive verbs and as a privative prefix (as in behead). The sense "on all sides, all about" naturally grew to include intensive uses (as in bespatter "spatter about," therefore "spatter very much," besprinkle, etc.). Be- also can be causative, or have just about any sense required. The prefix was productive 16c.-17c. in forming useful words, many of which have not survived, such as bethwack "to thrash soundly" (1550s) and betongue "to assail in speech, to scold" (1630s).
fuddle v.
1580s, "to get drunk" (intransitive); c. 1600, "to confuse as though with drink" (transitive), of obscure origin, perhaps from Low German fuddeln "work in a slovenly manner (as if drunk)," from fuddle "worthless cloth." The more common derivative befuddle dates only to 1873. Related: Fuddled; fuddling. A hard-drinker in 17c. might be called a fuddle-cap (1660s).