tweezers [M17th] In the 17th century a tweeze was a case of surgical instruments. It appears to be a shortened form of etweese, a plural of etui [E17th], which was a term for a small ornamental case for holding needles, cosmetics, and other articles, that came from French. In the mid 17th century tweeze was extended to tweezer, while the plural tweezes became tweezers. In the 1930s tweeze was re-formed from tweezers to mean ‘to pluck with tweezers’.