"by hand, by means of the hand," late 15c., from manual (adj.) + -ly (2).
Entries linking to manually
manual adj.
"of or pertaining to the hand; done, made, or used by hand;" c. 1400, from Latin manualis "of or belonging to the hand; that can be thrown by hand," from manus "hand, strength, power over; armed force; handwriting," from PIE root *man- (2) "hand." The military manual exercise (1760) is "the art of handling the rifle and other arms with precision and according to the prescribed method."
-ly 2
common adverbial suffix, forming from adjectives adverbs signifying "in a manner denoted by" the adjective, Middle English, from Old English -lice, from Proto-Germanic *-liko- (cognates: Old Frisian -like, Old Saxon -liko, Dutch -lijk, Old High German -licho, German -lich, Old Norse -liga, Gothic -leiko); see -ly (1). Cognate with lich, and identical with like (adj.).
Weekley notes as "curious" that Germanic uses a word essentially meaning "body" for the adverbial formation, while Romanic uses one meaning "mind" (as in French constamment from Latin constanti mente). The modern English form emerged in late Middle English, probably from influence of Old Norse -liga.