Old English ham "dwelling place, house, abode, fixed residence; estate; village; region, country," from Proto-Germanic *haimaz "home" (source also of Old Frisian hem "home, village," Old Norse heimr "residence, world," heima "home," Danish hjem, Middle Dutch heem, German heim "home," Gothic haims "village"), from PIE *(t)koimo-, suffixed form of root *tkei- "to settle, dwell, be home." As an adjective from 1550s. The old Germanic sense of "village" is preserved in place names and in hamlet.
'Home' in the full range and feeling of [Modern English] home is a conception that belongs distinctively to the word home and some of its Gmc. cognates and is not covered by any single word in most of the IE languages. [Buck]
Slang phrase make (oneself) at home "become comfortable in a place one does not live" dates from 1892 (at home "at one's ease" is from 1510s). To keep the home fires burning is a song title from 1914. To be nothing to write home about "unremarkable" is from 1907. Home movie is from 1919; home computer is from 1967. Home stretch (1841) is from horse racing (see stretch (n.)). Home economics as a school course first attested 1899; the phrase itself by 1879 (as "household management" is the original literal sense of economy, the phrase is etymologically redundant).
Home as the goal in a sport or game is from 1778. Home base in baseball attested by 1856; home plate by 1867. Home team in sports is from 1869; home field "grounds belonging to the local team" is from 1802 (the 1800 citation in OED 2nd ed. print is a date typo, as it refers to baseball in Spokane Falls). Home-field advantage attested from 1955.