"bottom, depths; base of an organ," 1754, from Latin fundus "bottom" (see fund (n.)). In any general use it probably is extended from specific senses in anatomy.
Entries linking to fundus
fund n.
1670s, "a bottom, the bottom; foundation, groundwork," from French fond "a bottom, floor, ground" (12c.), also "a merchant's basic stock or capital," from Latin fundus "bottom, foundation, piece of land" (from PIE root *bhudh- "bottom, base," source also of Sanskrit budhnah, Greek pythmen "foundation, bottom," Old English botm "lowest part;" see bottom (n.)). Meaning "stock of money or wealth available for some purpose" is from 1690s; sense of "store of anything to be drawn upon" is from 1704. Funds "money at one's disposal" is from 1728.