Donna

title of respect, 1520s, from Spanish or Portuguese Don, a title of respect prefixed to a man's Christian name, from Latin dominus "lord, master, owner" (from domus "house," from PIE root *dem- "house, household").

 It took on a general sense of "person of high importance or leading position," hence the English university sense "fellow of a college, any college authority" (c. 1660), originally student slang. The underworld sense is by 1952, from Italian don. The fem. form is Portuguese Dona, Spanish Doña, Italian Donna.

Proto-Indo-European root meaning "house, household." It represents the usual Indo-European word for "house" (Italian, Spanish casa are from Latin casa "cottage, hut;" Germanic *hus is of obscure origin).

It forms all or part of: Anno Domini; belladonna; condominium; dame; damsel; dan "title of address to members of religious orders;" danger; dangerous; demesne; despot; Dom Perignon; domain; dome; domestic; domesticate; domicile; dominate; domination; dominion; domino; don (n.) "Spanish, Italian, and Portuguese title of respect;" Donna; dungeon; ma'am; madam; madame; mademoiselle; madonna; major-domo; predominant; predominate; timber; toft.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit damah "house;" Avestan demana- "house;" Greek domos "house," despotēs "master, lord;" Latin domus "house," dominus "master of a household;" Armenian tanu-ter "house-lord;" Old Church Slavonic domu, Russian dom "house;" Lithuanian dimstis "enclosed court, property;" Old Norse topt "homestead."