distemper v.

word-forming element of Latin origin meaning 1. "lack of, not" (as in dishonest); 2. "opposite of, do the opposite of" (as in disallow); 3. "apart, away" (as in discard), from Old French des- or directly from Latin dis- "apart, asunder, in a different direction, between," figuratively "not, un-," also "exceedingly, utterly." Assimilated as dif- before -f- and to di- before most voiced consonants.

The Latin prefix is from PIE *dis- "apart, asunder" (source also of Old English te-, Old Saxon ti-, Old High German ze-, German zer-). The PIE root is a secondary form of *dwis- and thus is related to Latin bis "twice" (originally *dvis) and to duo, on notion of "two ways, in twain" (hence "apart, asunder").

In classical Latin, dis- paralleled de- and had much the same meaning, but in Late Latin dis- came to be the favored form and this passed into Old French as des-, the form used for compound words formed in Old French, where it increasingly had a privative sense ("not"). In English, many of these words eventually were altered back to dis-, while in French many have been altered back to de-. The usual confusion prevails.

As a living prefix in English, it reverses or negatives what it is affixed to. Sometimes, as in Italian, it is reduced to s- (as in spend, splay, sport, sdain for disdain, and the surnames Spencer and Spence).

late Old English temprian "to moderate, bring to a proper or suitable state, to modify some excessive quality, to restrain within due limits," from Latin temperare "observe proper measure, be moderate, restrain oneself," also transitive, "mix correctly, mix in due proportion; regulate, rule, govern, manage." This is often described as from Latin tempus "time, season" (see temporal), with a sense of "proper time or season." But as the root sense of tempus seems to be "stretch," the words in the "restrain, modify" sense might be from a semantic shift from "stretching" to "measuring" (compare temple (n.1)). Meaning "to make (steel) hard and elastic" is from late 14c. Sense of "tune the pitch of a musical instrument" is recorded from c. 1300. Related: Tempered; tempering.