disinterest n.

word-forming element of Latin origin meaning 1. "lack of, not" (as in dishonest); 2. "opposite of, do the opposite of" (as in disallow); 3. "apart, away" (as in discard), from Old French des- or directly from Latin dis- "apart, asunder, in a different direction, between," figuratively "not, un-," also "exceedingly, utterly." Assimilated as dif- before -f- and to di- before most voiced consonants.

The Latin prefix is from PIE *dis- "apart, asunder" (source also of Old English te-, Old Saxon ti-, Old High German ze-, German zer-). The PIE root is a secondary form of *dwis- and thus is related to Latin bis "twice" (originally *dvis) and to duo, on notion of "two ways, in twain" (hence "apart, asunder").

In classical Latin, dis- paralleled de- and had much the same meaning, but in Late Latin dis- came to be the favored form and this passed into Old French as des-, the form used for compound words formed in Old French, where it increasingly had a privative sense ("not"). In English, many of these words eventually were altered back to dis-, while in French many have been altered back to de-. The usual confusion prevails.

As a living prefix in English, it reverses or negatives what it is affixed to. Sometimes, as in Italian, it is reduced to s- (as in spend, splay, sport, sdain for disdain, and the surnames Spencer and Spence).

mid-15c., "legal claim or right; a concern; a benefit, advantage, a being concerned or affected (advantageously)," from Old French interest "damage, loss, harm" (Modern French intérêt), from noun use of Latin interest "it is of importance, it makes a difference," third person singular present of interresse "to concern, make a difference, be of importance," literally "to be between," from inter "between" (see inter-) + esse "to be" (from PIE root *es- "to be"). The sense development to "profit, advantage" in French and English is not entirely clear.

The earlier Middle English word was interesse (late 14c.), from Anglo-French interesse "what one has a legal concern in," from Medieval Latin interesse "compensation for loss," noun use of Latin interresse (compare German Interesse, from the same Medieval Latin source).

Financial sense of "money paid for the use of money lent" (1520s) earlier was distinguished from usury (illegal under Church law) by being in reference to "compensation due from a defaulting debtor." Sense of "personal or selfish consideration" is from 1620s. Meaning "business in which several people are interested" is from 1670s. Meaning "curiosity, feeling that something concerns one, appreciative or sympathetic regard" is first attested 1771. Interest group is attested from 1907; interest rate by 1868.