diffuse v.

word-forming element of Latin origin meaning 1. "lack of, not" (as in dishonest); 2. "opposite of, do the opposite of" (as in disallow); 3. "apart, away" (as in discard), from Old French des- or directly from Latin dis- "apart, asunder, in a different direction, between," figuratively "not, un-," also "exceedingly, utterly." Assimilated as dif- before -f- and to di- before most voiced consonants.

The Latin prefix is from PIE *dis- "apart, asunder" (source also of Old English te-, Old Saxon ti-, Old High German ze-, German zer-). The PIE root is a secondary form of *dwis- and thus is related to Latin bis "twice" (originally *dvis) and to duo, on notion of "two ways, in twain" (hence "apart, asunder").

In classical Latin, dis- paralleled de- and had much the same meaning, but in Late Latin dis- came to be the favored form and this passed into Old French as des-, the form used for compound words formed in Old French, where it increasingly had a privative sense ("not"). In English, many of these words eventually were altered back to dis-, while in French many have been altered back to de-. The usual confusion prevails.

As a living prefix in English, it reverses or negatives what it is affixed to. Sometimes, as in Italian, it is reduced to s- (as in spend, splay, sport, sdain for disdain, and the surnames Spencer and Spence).

Proto-Indo-European root meaning "to pour, pour a libation."

It forms all or part of: alchemy; chyle; chyme; confound; confuse; diffuse; diffusion; effuse; effusion; effusive; fondant; fondue; font (n.2) "complete set of characters of a particular face and size of type;" found (v.2) "to cast metal;" foundry; funnel; fuse (v.) "to melt, make liquid by heat;" fusible; fusion; futile; futility; geyser; gush; gust (n.) "sudden squall of wind;" gut; infuse; ingot; parenchyma; perfuse; perfusion; profuse; refund; refuse (v.) "reject, disregard, avoid;" refuse (n.) "waste material, trash;" suffuse; suffusion; transfuse; transfusion.

It is the hypothetical source of/evidence for its existence is provided by: Greek khein "to pour," khoane "funnel," khymos "juice;" Latin fundere (past participle fusus) "melt, cast, pour out;" Gothic giutan, Old English geotan "to pour;" Old English guttas (plural) "bowels, entrails;" Old Norse geysa "to gush;" German Gosse "gutter, drain."