derange v.

word-forming element of Latin origin meaning 1. "lack of, not" (as in dishonest); 2. "opposite of, do the opposite of" (as in disallow); 3. "apart, away" (as in discard), from Old French des- or directly from Latin dis- "apart, asunder, in a different direction, between," figuratively "not, un-," also "exceedingly, utterly." Assimilated as dif- before -f- and to di- before most voiced consonants.

The Latin prefix is from PIE *dis- "apart, asunder" (source also of Old English te-, Old Saxon ti-, Old High German ze-, German zer-). The PIE root is a secondary form of *dwis- and thus is related to Latin bis "twice" (originally *dvis) and to duo, on notion of "two ways, in twain" (hence "apart, asunder").

In classical Latin, dis- paralleled de- and had much the same meaning, but in Late Latin dis- came to be the favored form and this passed into Old French as des-, the form used for compound words formed in Old French, where it increasingly had a privative sense ("not"). In English, many of these words eventually were altered back to dis-, while in French many have been altered back to de-. The usual confusion prevails.

As a living prefix in English, it reverses or negatives what it is affixed to. Sometimes, as in Italian, it is reduced to s- (as in spend, splay, sport, sdain for disdain, and the surnames Spencer and Spence).

also *ker-, Proto-Indo-European root meaning "to turn, bend."

It forms all or part of: arrange; circa; circadian; circle; circuit; circum-; circumcision; circumflex; circumnavigate; circumscribe; circumspect; circumstance; circus; cirque; corona; crepe; crest; crinoline; crisp; crown;  curb; curvature; curve; derange;  flounce (n.) "deep ruffle on the skirt of a dress;" krone; ring (n.1) "circular band;" ranch; range; ranger; rank (n.) "row, line series;" research; recherche; ridge; rink; rucksack; search; shrink.

It is the hypothetical source of/evidence for its existence is provided by: Latin curvus "bent, curved," crispus "curly;" Old Church Slavonic kragu "circle;" perhaps Greek kirkos "ring," koronos "curved;" Old English hring "ring, small circlet."