"annoyance, petty vexation," 1788, noun of action from bother (q.v.).
Entries linking to botheration
bother v.
1718, also bauther, bather, bodder, "to bewilder, confuse;" 1745 as "give trouble to;" first in Irish writers (Sheridan, Swift, Sterne), hence probably from Anglo-Irish pother, which is perhaps from Irish bodhairim "I deafen." Related: Bothered; bothering. As a noun from 1803.