"drop, globule," 1725, from a verb meaning "to make or mark with blobs" (early 15c.), which is perhaps related to bubble. The same noun was used 16c. in senses of "a bubble, a blister." Related: Blobby.
Entries linking to blob
bubble n.
"small vesicle of water or some other fluid inflated with air or gas," early 14c., perhaps from Middle Dutch bobbel (n.) and/or Middle Low German bubbeln (v.), all probably of echoic origin. Figurative use in reference to anything wanting firmness, substance, or permanence is from 1590s. Specifically in reference to inflated markets or financial schemes originally in South Sea Bubble, which originated c. 1711 and collapsed 1720. Bubble-bath recorded by 1937. Bubble-shell is from 1847.
bleb n.
c. 1600, "blister or swelling," imitative. Also used for "bubble" (1640s), "protuberance on a cell surface" (1962). Compare blob. "In relation to blob, bleb expresses a smaller swelling" [OED].
glob n.
1900, perhaps suggested by blob, gob, etc. Also compare glop.