1590s, from un- (1) "not" + past participle of inform. Originally in reference to some specific matter or subject; general sense of "uneducated, ignorant" is recorded from 1640s.
Entries linking to uninformed
un- 1
prefix of negation, Old English un-, from Proto-Germanic *un- (source also of Old Saxon, Old Frisian, Old High German, German un-, Gothic un-, Dutch on-), from PIE *n- (source of Sanskrit a-, an- "not," Greek a-, an-, Old Irish an-, Latin in-), combining form of PIE root *ne- "not." Often euphemistic (such as untruth for "lie").
The most prolific of English prefixes, freely and widely used in Old English, where it forms more than 1,000 compounds. It underwent a mass extinction in early Middle English, but emerged with renewed vigor 16c. to form compounds with native and imported words. It disputes with Latin-derived cognate in- (1) the right to form the negation of certain words (indigestable/undigestable, etc.), and though both might be deployed in cooperation to indicate shades of meaning (unfamous/infamous), typically they are not.
It also makes words from phrases (such as uncalled-for, c. 1600; undreamed-of, 1630s; uncome-at-able, 1690s; unputdownable, 1947, of a book; un-in-one-breath-utterable, Ben Jonson; etc., but the habit is not restricted to un-; such as put-up-able-with, 1812). As a prefix in telegramese to replace not and save the cost of a word, it is attested by 1936.
inform v.
early 14c., "to train or instruct in some specific subject," from Old French informer, enformer "instruct, teach" (13c.) and directly from Latin informare "to shape, give form to, delineate," figuratively "train, instruct, educate," from in- "into" (from PIE root *en "in") + formare "to form, shape," from forma "form" (see form (n.)). In early use also enform until c. 1600. Sense of "report facts or news, communicate information to" first recorded late 14c. Related: Informed; informing.