1982, acronym formed from acquired immune deficiency syndrome. AIDS cocktail attested by 1997, the thing itself said to have been in use from 1995.
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acquired adj.
c. 1600, "gained by effort," past-participle adjective from acquire. Of diseases, "occurring after birth, thus not dependent on heredity," 1842 (opposed to congenital); acquired immune deficiency is attested by 1980; acquired immune deficiency syndrome by 1982. Acquired taste is attested from 1734.
immune adj.
mid-15c., "free, exempt" (from taxes, tithes, sin, etc.), from Latin immunis "exempt from public service, untaxed; unburdened, not tributary," literally "not paying a share," from assimilated form of in- "not, opposite of" (see in- (1)) + munis "performing services" (compare municipal), from PIE *moi-n-es-, suffixed form of root *mei- (1) "to change, go, move." Specific modern medical sense of "exempt (from a disease)," typically because of inoculation, is from 1881, a back-formation from immunity. Immune system attested by 1917.