sicken v.

Middle English sik, from Old English seoc "ill, unwell, diseased, feeble, weak; corrupt; sad, troubled, deeply affected by strong feeling," from Proto-Germanic *seuka-, which is of uncertain origin.

It is the general Germanic word (compare Old Norse sjukr, Danish syg, Old Saxon siok, Old Frisian siak, Middle Dutch siec, Dutch ziek, Old High German sioh, Gothic siuks "sick, ill"), but in German and Dutch it was displaced by krank "weak, slim," probably via the notion of "twisted, bent" (see crank (n.)).

The restricted meaning of English sick, "having an inclination to vomit, affected with nausea," is from 1610s. By c. 1200 as "distressed emotionally by grief, anger, etc.; physically ill through emotional distress. The sense of "tired or weary (of something), disgusted from satiety" is from 1590s; the figurative phrase sick and tired of is attested from 1783. To worry (oneself) sick is by 1952.

The modern colloquial meaning "mentally twisted" is by 1955, a revival of the word's use in this sense from 1550s (the sense of "spiritually or morally corrupt" was in Old English, which also had seocmod "infirm of mind"). Sick joke is attested by 1958.

word-forming element making verbs (such as darken, weaken) from adjectives or nouns, from Old English -nian, from Proto-Germanic *-inojan (also source of Old Norse -na), from PIE adjectival suffix *-no-. Most active in Middle English and early modern English, hence most verbs in -en are comparatively recent.

1725, "falling sick;" 1789, "causing revulsion, disgust, or nausea;" present-participle adjective from sicken. Related: Sickeningly.