sedative adj.

Proto-Indo-European root meaning "to sit."

It forms all or part of: assess; assiduous; assiento; assize; banshee; beset; cathedra; cathedral; chair; cosset; dissident; dodecahedron; Eisteddfod; ephedra; ephedrine; ersatz; icosahedron; inset; insidious; nest; niche; nick (n.) "notch, groove, slit;" nidicolous; nidification; nidus; obsess; octahedron; piezo-; piezoelectric; polyhedron; possess; preside; reside; saddle; sanhedrim; seance; seat; sedan; sedate; (adj.) "calm, quiet;" sedative; sedentary; sederunt; sediment; see (n.) "throne of a bishop, archbishop, or pope;" sessile; session; set (v.); sett; settle (n.); settle (v.); siege; sit; sitz-bath; sitzkrieg; size; soil (n.1) "earth, dirt;" Somerset; soot; subside; subsidy; supersede; surcease; tanist; tetrahedron; Upanishad.

It is the hypothetical source of/evidence for its existence is provided by: Sanskrit a-sadat "sat down," sidati "sits," nidah "resting place, nest;" Old Persian hadis "abode;" Greek ezesthai "to sit," hedra "seat, chair, face of a geometric solid;" Latin sedere "to sit; occupy an official seat, preside; sit still, remain; be fixed or settled," nidus "nest;" Old Irish suide "seat, sitting," net "nest;" Welsh sedd "seat," eistedd "sitting," nyth "nest;" Old Church Slavonic sežda, sedeti "to sit," sedlo "saddle," gnezdo "nest;" Lithuanian sėdėti "to sit;" Russian sad "garden," Lithuanian sodinti "to plant;" Gothic sitan, Old English sittan "to sit."

"quieting excessive action," by 1831, from French calmatif; see calm (adj.) + -ative. A Greek-Latin hybrid; purists prefer sedative, but OED writes that "The Latinic suffix is here defensible on the ground of It. and Sp. calmar, F. calmer ...." Also as a noun, "a quieting drug" (1847).

"treat with sedatives," by 1945, a verb to go with the noun derivative of sedative (adj.). The word also existed 17c. in English with a sense of "make calm or quiet." Related: Sedated (by 1953 as an adjective, "under the influence of a sedative drug"); sedating.