synthetic compound used as a local anesthetic, 1918, from pro- + cocaine.
Entries linking to procaine
pro-
word-forming element meaning "forward, forth, toward the front" (as in proclaim, proceed); "beforehand, in advance" (prohibit, provide); "taking care of" (procure); "in place of, on behalf of" (proconsul, pronoun); from Latin pro (adv., prep.) "on behalf of, in place of, before, for, in exchange for, just as," which also was used as a first element in compounds and had a collateral form por-.
Also in some cases from cognate Greek pro "before, in front of, sooner," which also was used in Greek as a prefix (as in problem). Both the Latin and Greek words are from PIE *pro- (source also of Sanskrit pra- "before, forward, forth;" Gothic faura "before," Old English fore "before, for, on account of," fram "forward, from;" Old Irish roar "enough"), extended form of root *per- (1) "forward," hence "in front of, before, toward, near," etc.
The common modern sense of "in favor of, favoring" (pro-independence, pro-fluoridation, pro-Soviet, etc.) was not in classical Latin and is attested in English from early 19c.
cocaine n.
alkaloid obtained from the leaves of the coca plant, 1874, from Modern Latin cocaine (1856), coined by Albert Niemann of Gottingen University from coca (from Quechua cuca) + chemical suffix -ine (2). A medical coinage, the drug was used 1870s as a local anaesthetic for eye surgery, etc. "It is interesting to note that although cocaine is pronounced as a disyllabic word it is trisyllabic in its formation" [Flood]. Cocainism "addiction to cocaine" is recorded by 1885.