populate v.

c. 1300, peple, "humans, persons in general, men and women," from Anglo-French peple, people, Old French pople, peupel "people, population, crowd; mankind, humanity," from Latin populus "a people, nation; body of citizens; a multitude, crowd, throng," a word of unknown origin. Based on Italic cognates and derivatives such as populari "to lay waste, ravage, plunder, pillage," Populonia, a surname of Juno, literally "she who protects against devastation," the Proto-Italic root is said to mean "army" [de Vaan]. An Etruscan origin also has been proposed. The Latin word also is the source of Spanish pueblo, Italian popolo. In English, it displaced native folk.

Sense of "Some unspecified persons" is from c. 1300. Meaning "body of persons comprising a community" is by mid-14c. (late 13c. in Anglo-French); the meaning "common people, masses" (as distinguished from the nobility) is from late 13c. The meaning "members of one's family, tribe, or clan" is from late 14c.

The word was adopted after c. 1920 by Communist totalitarian states, according to their opponents to give a spurious sense of populism to their governments. It is based on the political sense of the word, "the whole body of enfranchised citizens (considered as the sovereign source of government power," attested from 1640s. This also is the sense in the legal phrase The People vs., in U.S. cases of prosecution under certain laws (1801).

The people are the only censors of their governors: and even their errors will tend to keep these to the true principles of their institution. To punish these errors too severely would be to suppress the only safeguard of the public liberty. The way to prevent these irregular interpositions of the people is to give them full information of their affairs thro’ the channel of the public papers, and to contrive that those papers should penetrate the whole mass of the people. [Jefferson to Edward Carrington, Jan. 16, 1787]

People of the Book "those whose religion entails adherence to a book of divine revelation" (1834) translates Arabic Ahl al-Kitab. 

"deprive of inhabitants," 1540s; see de- + populate. Perhaps from Latin depopulatus, past participle of depopulari "to lay waste, ravage." Related: Depopulated; depopulating. Earlier in same sense was dispeplen (early 15c.).