inflect v.

word-forming element meaning "not, opposite of, without" (also im-, il-, ir- by assimilation of -n- with following consonant, a tendency which began in later Latin), from Latin in- "not," cognate with Greek an-, Old English un-, all from PIE root *ne- "not."

In Old French and Middle English often en-, but most of these forms have not survived in Modern English, and the few that do (enemy, for instance) no longer are felt as negative. The rule of thumb in English has been to use in- with obviously Latin elements, un- with native or nativized ones.

early 15c., "capable of being bent; mentally or spiritually pliant," from Old French flexible or directly from Latin flexibilis "that may be bent, pliant, flexible, yielding;" figuratively "tractable, inconstant," from flex-, past participle stem of flectere "to bend," which is of uncertain origin. Flexile (1630s) and flexive (1620s) have become rare. Related: Flexibly. Coles' dictionary (1717) has flexiloquent "speaking words of doubtful or double meaning."